Click HERE to learn more about our MEMORIAL DAY SALE!

Talk to an Oxygen Specialist:

1-800-775-0942

Why Choose Us?

Portable Oxygen Concentrators ON SALE - Discounted!

18 products
  • Inogen® Rove 6 Portable Oxygen Concentrator, Standard Battery - Main Clinic Supply
    from $3,295.00
    from $3,295.00
    Out of Stock
  • CAIRE Freestyle Comfort Portable Oxygen Concentrator - Main Clinic Supply
    from $2,795.00
    from $2,795.00
    Out of Stock
  • Drive Devilbiss iGO2 - Portable Oxygen Concentrator - Main Clinic Supply
    from $2,995.00
    from $2,995.00
    Out of Stock
  • Inogen One® Rove 4 Portable Oxygen Concentrator, Standard Battery - Main Clinic Supply
    from $2,995.00
    from $2,995.00
    Out of Stock
  • CAIRE SeQual Eclipse 5 - Portable Oxygen Concentrator - Main Clinic Supply
    from $3,200.00
    from $3,200.00
    Out of Stock
  • O2 Concepts OxLife Independence Portable Oxygen Concentrator - Main Clinic Supply
    from $3,195.00
    from $3,195.00
    Out of Stock
  • Inogen One G5 Portable Oxygen Concentrator - Main Clinic Supply
    from $1,995.00
    from $1,995.00
    Out of Stock
  • Inogen One G4 Portable Oxygen Concentrator - Main Clinic Supply
    from $2,744.00
    from $2,744.00
    Out of Stock
  • Inogen® Rove 6 Portable Oxygen Concentrator and Inogen At Home® Stationary Oxygen Concentrator Bundle - Main Clinic Supply
    from $4,767.00
    from $4,767.00
    Out of Stock

Lasted Updated: 1-12-2025 

Portable Oxygen Concentrators: Reviews, FAQs, and Top Models for 2025

Those with respiratory conditions who need a portable oxygen concentrator (POC) for the first time may initially feel overwhelmed by the many choices.

While most on-the-go portable oxygen concentrators are lightweight and efficient, they can differ significantly from model to model.

Our collection summary gives you an overview of our portable oxygen concentrator specifications.

Portable oxygen concentrators (POCs) provide an innovative solution for oxygen therapy, combining mobility and convenience. Explore the answers to common questions below and learn how to choose the best device for your needs.

 

(FAQ) Frequently Asked Questions: Portable Oxygen Concentrators

Best Portable Oxygen Concentrators - 2025 Models

When looking for the best portable oxygen concentrator in 2024, Main Clinic Supply is excited to announce early access to the Inogen Rove 4. This highly anticipated model is now available ahead of its official 2025 release!

Additionally, the Inogen One Rove 6 and the GCE Zen-O are excellent options that continue to push the boundaries of portable oxygen therapy.

  • Inogen Rove 4: Ultra-lightweight design, 3.5 pounds, 8-hour battery life.
  • Inogen One Rove 6: Intelligent Oxygen Delivery, up to 12-hour battery life, FAA approved.
  • GCE Zen-O: Constant-flow oxygen, versatile for travel and home use, FAA approved.

Featured Lightweight Portable Oxygen Concentrators Comparison Chart

Feature Inogen One Rove 6 Inogen Rove 4 (2025) GCE Zen-O
Weight 4.8 pounds 3.5 pounds 10 pounds
Sound level 38 decibels 39 decibels 42 decibels
Battery life Up to 12 hours Up to 8 hours (est.) Up to 8 hours
Flow settings 1-6 1-4 (est.) Pulse & Constant Flow
Size L: 8.18", W: 3.26", H: 8.15" L: 5.9 x W: 2.7 x H: 7.5 in L: 12.3", W: 8.3", H: 8.3"
Exclusive Technology Intelligent Oxygen Delivery Intelligent Oxygen Delivery Rate Responsive Therapy™ (RRT)
FAA Approved Yes Yes Yes
Power Features AC/DC power supply for worldwide use AC/DC AC/DC power supply, continuous flow


Featured High-Flow-Oxygen Portable Oxygen Concentrators Comparison Chart

Feature Oxlife Independence Caire SeQual Eclipse 5
Weight 16.7 lbs (device only); 18.9 lbs with cart 18.4 lbs (device + battery)
Sound Level 45.5–51.8 dBA 40–48 dBA
Battery Life Up to 6 hours (2 batteries in pulse mode) Up to 5 hours (pulse mode)
Flow Settings Continuous: 0.5–3 LPM
Pulse: 0.5–6		 Continuous: 0.5–3 LPM
Pulse: 1–9
Size H: 20.29", W: 10.85", D: 9.45" H: 19.3", W: 12.3", D: 7.1"
Exclusive Technology Dynamic Network Analysis (DNA) autoSAT® Technology
FAA Approved Yes Yes
Power Features AC/DC Power, Rechargeable Battery AC/DC Power, Rechargeable Battery

 

Why Choose Main Clinic Supply? Trusted Support and Service for Your Portable Oxygen Needs

Exclusive First-Release Access to New Portable Oxygen Concentrators

At Main Clinic Supply, we’re proud to be among the first to offer early access to the Inogen Rove 4. We specialize in providing the latest technology in portable oxygen concentrators, including exclusive access to new releases. Our range of portable oxygen concentrators caters to various needs, helping our customers confidently maintain their active lifestyles.

Explore our full collection to find the best portable oxygen concentrator for you, and take advantage of early access to the Inogen Rove 4!

 

Authorized Dealer for Portable Oxygen Concentrator For Diverse Brands and Models

Inogen One Portable Oxygen Concentrators

CAIRE Portable Oxygen Concentrators

Resources

Inogen Rove 6™ User Manual - Updated

Comprehensive guide to using the Inogen Rove 6 portable oxygen concentrator.

Inogen Rove 6 - Quick Start Video

A step-by-step video tutorial to get started with your Inogen Rove 6 device.

Inogen Rove 4™ User Manual - Updated

Detailed instructions for operating the Inogen Rove 4 portable oxygen concentrator.

Inogen Rove 4 - Quick Start Video

Learn the basics of setting up and using the Inogen Rove 4 with this quick start video.

Inogen G5 Manual - Updated

Updated manual for the Inogen G5 portable oxygen concentrator.

Inogen G4 Manual - Updated

Complete guide to the Inogen G4 portable oxygen concentrator.

CAIRE Freestyle Comfort Manual - Updated

Latest manual for the CAIRE Freestyle Comfort oxygen concentrator.

CAIRE Freestyle Comfort - Quick Start Video

A quick start video to help you get familiar with the CAIRE Freestyle Comfort device.

Customer Success Stories: Why People Love Main Clinic Supply for Portable Oxygen Concentrators

Eloise D. (IL)

"Everything went so smooth when ordering my oxygen concentrator. Dylan was super nice and explained everything to me."

Linda L. (KY)

"I have been a customer for over 5 years. I have had repair needs as well as annual cleaning and upgrades to the system and never had any problems. I have had overnight service on all occasions. Thank you for being there."

Jerry H. (MO)

"Being without the ability to breathe on your own causes extreme anxiety. Needing help and being able to get it fast without delay is wonderful. They helped me so well and so fast my anxiety was diminished. Thank you."

Patrick W. (FL)

"Leo was efficient in getting my order for a backup concentrator processed and on its way. The service department promptly answered all of my questions. Great service all around."

 George A. (HI)

"Excellent fast service. My third purchase from Main Clinic Supply and all experiences have been outstanding."

 

© 2025 Main Clinic Supply. All Rights Reserved.


Inogen Portables Starting at $1395

Please complete below to access our best deals

*By submitting this information, I authorize MCS to contact me including by phone.
✔

THANK YOU!

Prices have now changed.
Click OK to see and order at a much lower price, for a limited time!

Limited time only

We cannot advertise prices below the Manufacturer's list price, but since you asked directly, we can offer you a much lower price.

OK
✔

THANK YOU!

Your request has been received. Manufacturers only allow us to show MINIMUM Advertised Price so we will have your personal Portable Oxygen Specialist contact you to help answer any questions and provide you with today’s best pricing.
When you receive a call from caller ID “Oxygen Agent” or a "1-800 number", this is Main Clinic Supply calling to assist you.

OK
Call To Talk To An Oxygen Specialist
1-800-775-0942
Get up to $1100 OFF