Portable Oxygen Concentrators for Home Use
For many patients with chronic respiratory conditions, access to supplemental oxygen is a necessity. Stationary oxygen concentrators are useful for these conditions as they provide continuous flows of oxygen so that the effects of conditions like chronic obstructive pulmonary disease (COPD) and bronchiectasis are treated. However, these stationary units have their limits, especially when the patient wants to live an active lifestyle.
This is where portable oxygen concentrators come in as an alternative. More than just their use as a travel option, these concentrators are compact, efficient, and have the power to be easily used at home. This offers patients heightened independence without compromising their vital oxygen supply.
Our Oxygen Concentrators for Home Use
At Main Clinic Supply, we offer multiple portable oxygen concentrators that provide both continuous oxygen and intelligent, as-needed oxygen flows. These are useful for patients who want to stay active, and our continuous flow portable oxygen concentrators are all FAA-approved for use in airplanes. Here’s a quick rundown of the devices we have on offer here at Main Clinic Supply.
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Inogen® Rove 6 Portable Oxygen Concentrator, Standard Battery
Inogen® Rove 6 Portable Oxygen Concentrator, Standard Battery
- Intelligent Pulse Flows 1 to 6
- Most Updated Software
- Only 4.7 pounds
- FAA Airline Approved
- Quiet Operation
- Longest Battery Life
- Regular price
- from $2,995.00
- Sale price
- from $2,995.00
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Inogen One® G3® Portable Oxygen Concentrator, Standard Battery
Inogen One® G3® Portable Oxygen Concentrator, Standard Battery
- Intelligent Pulse Flows 1 to 5
- Only 4.8 pounds
- FAA Airline Approved
- Regular price
- from $1,995.00
- Sale price
- from $1,995.00
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Oxlife Liberty2 - True Continuous Flow Portable Oxygen
Oxlife Liberty2 - True Continuous Flow Portable Oxygen
- Constant Flow .5-2 LPM
- Pulse Flow Settings 1-10
- Only 7.8 Pounds
- FAA Approved
- “True Constant Flow up to 2 LPM”
- CPAP compatible
Call for Deals -
GCE Zen-O Portable Oxygen Concentrator
GCE Zen-O Portable Oxygen Concentrator
- Constant Flow up to 2 LPM and Pulse Dose 1-6
- Long Battery Life
- FAA Airline Approved
- Carry Bag and Case Included
- CPAP compatible
Call for Deals -
O2 Concepts OxLife Independence Portable Oxygen Concentrator
O2 Concepts OxLife Independence Portable Oxygen Concentrator
- Up to 3 LPM True Constant Flow/Pulse Dose 1 to 6
- FAA Airline Approved
- Built-In Mobile Cart
- 5 Year Machine Warranty
- CPAP Compatible
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Inogen® Rove 6 Portable Oxygen Concentrator
Inogen® Rove 6 Portable Oxygen Concentrator
- Intelligent Pulse Flows 1 to 6
- Only 4.7 pounds
- FAA Airline Approved
- Quiet Operation
- Long Battery Life
Call for Deals -
Inogen One® Rove 4 Portable Oxygen Concentrator, Standard Battery
Inogen One® Rove 4 Portable Oxygen Concentrator, Standard Battery
- Intelligent Pulse Flows 1 to 4
- Only 2.8 pounds
- FAA Airline Approved
- Smallest with Most Oxygen Output
Call for Deals -
Inogen® Rove 6 Portable Oxygen Concentrator and Inogen At Home® Stationary Oxygen Concentrator Bundle
Inogen® Rove 6 Portable Oxygen Concentrator and Inogen At Home® Stationary Oxygen Concentrator Bundle
- Travel with Both
- Daytime Portable Flows 1 -6
- Nighttime Constant Flow 1 - 5 LPM
- POC-FAA Airline Approved
- Attractive Travel Case
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CAIRE SeQual Eclipse 5 - Portable Oxygen Concentrator
CAIRE SeQual Eclipse 5 - Portable Oxygen Concentrator
- Constant Flow up to 3 LPM, Pulse Dose Settings 1 to 9
- AutoSAT Technology
- FAA Airline Approved
- Extended Battery Life
- CPAP Compatible
Call for Deals -
CAIRE Freestyle Comfort Portable Oxygen Concentrator
CAIRE Freestyle Comfort Portable Oxygen Concentrator
- Pulse Flow 1 - 5
- 5 Pounds, Lightweight and Comfortable
- FAA Airline Approved
- Long Battery Life
- “UltraSense Technology”- Adjust Oxygen Bolus
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GCE Zen-O Lite Portable Oxygen Concentrator
GCE Zen-O Lite Portable Oxygen Concentrator
- Pulse Dose Settings 1-5
- FAA Airline Approved
- Low Sound Level
- Low Effort Servicing
Call for Deals -
Drive Devilbiss iGO2 - Portable Oxygen Concentrator
Drive Devilbiss iGO2 - Portable Oxygen Concentrator
- Pulse Dose Settings 1 to 5
- 5 lbs, Durable and Quiet Operation
- Ultra Sensitive Conserving Trigger
- SmartDose Technology- automatically adjust your oxygen setting
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Rhythm P2-E6 Portable Oxygen Concentrator
Rhythm P2-E6 Portable Oxygen Concentrator
- Regular price
- from $3,295.00
- Sale price
- from $3,295.00
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Inogen One® Rove 4 Portable Oxygen Concentrator + Inogen At Home® Stationary Oxygen Concentrator Bundle
Inogen One® Rove 4 Portable Oxygen Concentrator + Inogen At Home® Stationary Oxygen Concentrator Bundle
- Travel with Both
- Daytime Portable Flows 1 -4
- Nighttime Constant Flow 1 - 5 LPM
- POC-FAA Airline Approved
- Attractive Travel Case
- Regular price
- from $4,308.00
- Sale price
- from $4,308.00
- Regular price
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On Sale Out of Stock
Why Buy a Portable Oxygen Concentrator for Home Use: Space-Saving, Power-Ready, and Total Mobility
Many people assume that a stationary home oxygen concentrator is the best solution for in-home oxygen therapy. However, portable oxygen concentrators (POCs) are quickly becoming the preferred option, even for everyday use around the house. Originally built for travel, these powerful and compact devices offer key advantages that go far beyond mobility.
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Portable Oxygen Concentrators Save Space in Your Home
Portable oxygen concentrators are designed to be compact and lightweight, making them ideal for smaller homes, apartments, or shared living spaces. Devices like the Inogen Rove 6 weigh under six pounds—lighter than most purses—and can easily be carried from room to room. There’s no bulky frame, no wheels to roll over carpet, and no need to designate an entire corner of your home for an oxygen machine.
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Freedom to Move Without Long Oxygen Tubing
One of the biggest frustrations with traditional home oxygen concentrators is the need for long tubing that snakes through your house. It gets tangled on furniture, poses a tripping risk, and limits where you can go. A portable oxygen concentrator moves with you, eliminating the need for 25 or 50 feet of tubing. This means you can:
- Clean the house without dragging cords
- Go outside to water plants or walk the dog
- Move between rooms without unhooking
- Relax on the porch or in a different chair without rearranging anything
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Battery Power for Peace of Mind During Power Outages
Unlike stationary units that shut off during power failures, portable oxygen concentrators come with rechargeable batteries and every model recommended by Main Clinic Supply includes a DC power adapter for use in vehicles or with backup power supplies. This is a huge benefit in areas prone to:
- Storms or hurricanes
- Rolling blackouts
- Winter weather-related outages
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Much Quieter Than Traditional Home Units
Older home oxygen concentrators can be loud and intrusive, especially when they run continuously in small or shared spaces. Portable oxygen concentrators are designed to operate with minimal sound, making them ideal for resting, watching TV, or spending time with others without the hum or drone of a full-sized machine.
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Dual Use: Great for Home and Perfect for Travel
When you choose a portable oxygen concentrator, you’re getting more than just a home-use device—you’re getting a machine that can travel with you. Most models are FAA-approved for air travel and include features like:
- Pulse dose or continuous flow delivery
- Lightweight, airline-friendly design
- Rechargeable batteries and DC/car adapters
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Simple to Use, Easy to Maintain, and Cost-Efficient
Portable oxygen concentrators come with intuitive controls and displays, rechargeable batteries with clear indicators, long-lasting filters, and minimal maintenance needs. In the long run, owning your own POC for home use can save hundreds or even thousands of dollars compared to renting a unit when needed.
Key Features to Look for in a Home Portable Oxygen Concentrator
Feature | Why It Matters |
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Size and Portability | A smaller, lightweight oxygen concentrator makes daily life significantly easier. Compact models can be worn over the shoulder or carried like a handbag. |
Quiet Operation | Typically around 48–49 dBA—about the sound of a quiet conversation—allowing restful, unobtrusive therapy. |
Battery Life & Power Backup | Look for at least 5 hours of use per charge and the inclusion of a DC car adapter for charging during outages or travel. |
Oxygen Delivery Type | Choose between pulse dose and dual-mode (pulse + continuous) based on your needs for daytime mobility and nighttime therapy. |
Patients Don’t Have to Lose Mobility with a Portable Oxygen Concentrator
When dealing with a respiratory condition, lifestyles don’t have to change. With a portable oxygen concentrator, patients can maintain an active lifestyle without being adversely affected by their oxygen requirements. At Main Clinic Supply, we offer a wide range of portable oxygen concentrators that can be used both at home and on the go. Should assistance be required in determining the optimal model or configuration, expert Oxygen Specialists stand ready to provide guidance and support for a confident selection.
Contact us today at 1-888-850-9017 for assistance in choosing the right portable oxygen concentrator for your needs.
Speak To One Of Our Oxygen Specialists!


“This has been the best online buying experience I have ever done, unlike other places when I was shopping and reading reviews Main Clinic Supply answered the phone right away every time, my package said overnight before 10:30 AM, it was here 10.15 AM the next day! Can’t say enough good thing, they realize you need your oxygen now they get it to you fast!”
Get our Ultimate Freedom Package!
Save big with our freedom package and get the Inogen One Rove 6—the latest in portable oxygen technology—along with the Inogen At-Home Oxygen Concentrator, plus a free travel case.
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