Why Choose Us?

About Us & What Recent Customers Said.......

Main Clinic Supply is a family-owned medical service based in Rochester, Minnesota, the home of the world-famous Mayo Clinic.

Inspired by the values of our community, we follow a simple mission:

"The Needs of the Patient Come First."

Recent Reviews and Testimonials - 4.9 out of 5.0 Rating

What Makes Main Clinic Supply Different

For over 23 years (since the dawn of portable oxygen technology), we have focused exclusively on providing the latest and most advanced systems at the lowest possible prices. As an authorized dealer and service center for all the top brands, we work directly with the manufacturers to bring you genuine parts, full warranties, and the latest products. But we do more than sell. Our authorized sale and service center in Rochester, Minnesota, home of the Mayo Clinic, is staffed by factory trained technicians who test, and repair machines every day.
When you call us, you are talking to people who actually know these machines inside and out and genuinely care about the people relying on these machines.

Top 5 Portable Oxygen Concentrators for Travel in 2026

Our expert rankings of the best travel POCs based on weight, battery life, oxygen output, noise level, and FAA approval status.

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Portable Oxygen Concentrator Battery Life Guide

A complete breakdown of battery durations for every major POC model, plus tips for maximizing battery life while traveling.

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Call To Talk To An Oxygen Specialist
1-800-775-0942
Get up to $1100 OFF