Collection: CPAP & BiPAP Machines for Sale
Sleep apnea and respiratory support
Main Clinic Supply has a comprehensive range of CPAP and BiPAP machines to help users breathe more easily and experience a more restful sleep cycle. Whether you're managing obstructive sleep apnea, central sleep apnea, or another respiratory condition, our selection includes some of the industry's latest models with advanced comfort and safety features.
It's important to call us directly for pricing. Most manufacturers don't allow us to advertise prices online, but we share our lowest prices with you over the phone. This means you'll often get a better deal than what you might expect or see elsewhere. Give us a quick call at 1-800-775-0942.
Fast Facts: CPAP & BiPAP machines
- Prescription required: CPAP and BiPAP machines are FDA-cleared medical devices that require a valid prescription.
- CPAP vs BiPAP: CPAP delivers one constant pressure; BiPAP delivers two (higher for inhale, lower for exhale).
- Brands we carry: ResMed (AirSense, AirCurve, AirMini), Respironics (DreamStation 2), and Luna (TravelPAP).
- Warranty: Each machine comes with a standard 2-year warranty. Bundles include humidifiers, masks, tubing, and travel bags.
Our CPAP and BiPAP oxygen machines
If you have sleep apnea or another condition that affects your breathing — like Chronic Obstructive Pulmonary Disease (COPD) — your health practitioner may have prescribed a PAP machine with oxygen. "PAP" stands for Positive Air Pressure.
The air pressure generated by the machine helps keep your airway open and prevents it from collapsing, supplementing with medical-grade oxygen throughout the night to increase your blood oxygen levels.
Main Clinic Supply has several quality devices if a PAP machine is critical to your health and well-being. Here's a full list of the CPAP and BiPAP oxygen machines available at Main Clinic Supply:
Featured CPAP and BiPAP machines at Main Clinic Supply
Below is a comparison of the most popular CPAP and BiPAP devices available at Main Clinic Supply. This table lets you quickly compare key features and identify the right machine for your specific needs.
| Product | Type | Pressure range | Humidification | Travel friendly | Unique features |
|---|---|---|---|---|---|
| ResMed AirMini AutoSet CPAP | CPAP / APAP / AutoSet for Her | 4–20 cm H2O | Waterless HumidX™ | Yes | Smallest CPAP device; Bluetooth connectivity |
| ResMed AirSense 10 AutoSet CPAP with HumidAir | CPAP / APAP / AutoSet for Her | 4–20 cm H2O | Integrated heated HumidAir™ | Yes | ClimateLineAir™ tubing; AutoRamp™ |
| ResMed AirCurve 10 VAuto BiLevel with HumidAir | BiPAP / Auto BiLevel | 3–25 cm H2O | Integrated heated HumidAir™ | Yes (with travel bag) | VAuto mode; Vsync leak management |
| ResMed AirCurve 10 ASV BiLevel with HumidAir | BiPAP / ASV | 3–25 cm H2O | Integrated heated HumidAir™ | Yes (with travel bag) | Adaptive Servo-Ventilation (ASV) |
| Respironics DreamStation 2 Auto CPAP with Humidifier | CPAP / APAP | 4–20 cm H2O | Integrated heated | Yes | Ramp Plus; FLEX™ technology |
| ResMed AirSense 11 AutoSet CPAP with HumidAir | CPAP / APAP / AutoSet for Her | 4–20 cm H2O | Integrated heated HumidAir™ | Yes | Touchscreen; myAir™ app |
| ResMed AirCurve 11 VAuto BiLevel with HumidAir | BiPAP / Auto BiLevel | 3–25 cm H2O | Integrated heated HumidAir™ | Yes | Easy-Breathe waveform |
| Luna TravelPAP | CPAP / APAP (Travel) | 4–20 cm H2O | Integrated or optional | Yes | Ultra-portable design |
The difference between CPAP and BiPAP machines
To understand what conditions may require each type of machine, it helps to understand how each one works to make breathing easier. The difference between CPAP and BiPAP is straightforward — it comes down to how the device manages pressure.
EPAP: Lower pressure level provided during exhalation.
| CPAP | BiPAP |
|---|---|
| Delivers a single, constant pressure during sleep | Delivers two pressures: higher for inhaling, lower for exhaling |
| Best for obstructive sleep apnea | Best for central/complex sleep apnea, COPD, and higher pressure needs |
| Features: ramp, humidification, auto-adjust | Features: pressure relief, auto-adjust, flexibility |
| Compact; travel options available | Slightly larger, but portable options exist |
| Widely covered by insurance | Covered for specific diagnoses |
Frequently asked questions
What is AutoSet for Her?
AutoSet for Her is a feature in specific ResMed CPAP devices designed to address the unique breathing patterns of women, offering more tailored sleep apnea therapy.
Do I need a prescription for a CPAP or BiPAP machine?
Yes. A valid prescription is required for any CPAP or BiPAP machine. These are FDA-cleared medical devices.
Can I travel with a CPAP or BiPAP machine?
Yes. All models Main Clinic Supply carries are travel-friendly, and the ResMed AirMini and Luna TravelPAP are specifically designed for portability.
Rely on Main Clinic Supply for all CPAP or BiPAP needs
At Main Clinic Supply, we provide expert guidance to help you select the right device and accessories for your prescription and lifestyle. We offer an extensive selection of CPAP and BiPAP machines, each accompanied by a standard 2-year warranty. We also offer several convenient bundles that include humidifiers, masks, tubing, and travel bags. Many of our products include free shipping via FedEx.
For more details or to speak with a specialist, call 1-800-775-0942 — or explore each product page for in-depth specifications and user guides.
Disclaimer: CPAP and BiPAP machines are FDA-cleared medical devices that require a valid prescription. Always work with your physician on prescribed pressure settings, mask selection, and overall sleep apnea or respiratory care plan. This page is for informational purposes only and is not medical advice.