10 Liter Oxygen Concentrators
For patients who require more than 5 LPM of continuous oxygen flow, our 10 LPM home oxygen concentrators deliver reliable, medical-grade performance, designed for long-term use. These high-capacity units support a wide range of clinical needs, whether for significant respiratory conditions, multiple patients, or specialized equipment setups.
All machines are new, include full warranties, and are backed by expert support from Main Clinic Supply.
5-liter Oxygen Concentrators
If you’re in the market to buy a 10-liter oxygen machine for home use, Main Clinic Supply offers three sturdy models:
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Drive DeVilbiss 10 Liter Compact Oxygen Concentrator
Drive DeVilbiss 10 Liter Compact Oxygen Concentrator
- Regular price
- from $1,399.00
- Sale price
- from $1,399.00
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On Sale Out of Stock -
React Health Platinum 10 Home Oxygen Concentrator with SENSEO2 Oxygen Purity System
React Health Platinum 10 Home Oxygen Concentrator with SENSEO2 Oxygen Purity System
- Regular price
- from $1,645.00
- Sale price
- from $1,645.00
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- Unit price
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On Sale Out of Stock -
Philips Respironics Millennium M10 Oxygen Concentrator
Philips Respironics Millennium M10 Oxygen Concentrator
- Regular price
- from $1,495.00
- Sale price
- from $1,495.00
- Regular price
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On Sale Out of Stock
Considerations When Buying a 10-Liter Oxygen Concentrator
There are several important factors to keep in mind when selecting a 10 LPM concentrator for home use:
Oxygen Concentration Level
Oxygen concentration is the amount of oxygen delivered to the patient after being compressed and filtered in the concentrator. It is typically measured as a percentage.
Oxygen concentration is determined by the design of the filtration system, the number of filters in the machine, and the concentrator’s nitrogen-removing sieve system.
Our React Health Platinum 10 Home Oxygen Concentrator and Philips Respironics Millennium M10 with OPI Oxygen Concentrator offer an impressive 95% oxygen at a continuous flow rate of 2-10 LPM
Oxygen Outlet Pressure
Oxygen concentrators for home use are designed to be stationary. If you prioritize mobility, then oxygen outlet pressure is essential.
The higher the outlet pressure, the longer the oxygen tubing can be from the machine to you, without compromising flow or purity. This gives you the freedom to move throughout your home or even into adjacent outdoor spaces. The Drive DeVilbiss 10 Liter Compact, for example, delivers an impressive 20 PSI outlet pressure, which supports oxygen tubing runs of up to 50 feet or more. That means greater mobility and fewer disruptions during therapy, even if your concentrator is positioned across the house.
Sound Levels
The sound levels of an oxygen concentrator are a significant factor for most people using supplementary oxygen, particularly if the concentrator will be used in a shared living space or when the patient or family of the patient are sleeping.
For the 10 LMP devices we offer, sound ranges are typically around 50 dBA, which is lower than the sound output of a typical refrigerator.
Weight and Size
Weight and size are important considerations, especially if there’s a need to move the concentrator around the home. Many people do not have the strength to move bulky machines from room to room. Large concentrators take up space in a home, and moving them can damage door jams, walls, and furniture.
The Philips Respironics Millennium M10 has a compact design and measures 19” wide x 27” high and 13” deep. The unit weighs 53 lbs and with its streamlined integrated handle and strong castor wheels, it is easy to move from room to room.
The Drive DeVilbiss 10 Liter Compact is one of the lightest and quietest continuous-flow 10-liter oxygen concentrators on the market. Weighing only 42 lbs and standing 24.5” tall, it is smaller than most other 10-liter concentrators as well.
Oxygen concentrators can range significantly in size and portability, so shop around. Not all concentrators are as compact or have casters for easy movement.
Dependability and Warranty
Oxygen concentrators in the U.S. have a reputation for excellent quality. When purchasing an oxygen machine for home use, patients and their caregivers typically want a reliable product that lasts.
At Main Clinic Supply, our home oxygen concentrators come with a standard three-year warranty with an option to upgrade to a lifetime warranty.
An extended warranty reflects our commitment to quality construction and confidence in the products we sell.
Comparing Main Clinic Supply’s 10-Liter Oxygen Concentrators
When patients require higher oxygen output, such as for advanced respiratory conditions or specialized equipment, a 10-liter home oxygen concentrator can provide the continuous flow necessary to support those needs. Main Clinic Supply offers several high-quality, medical-grade 10 LPM models designed for around-the-clock use. Below is a side-by-side comparison of our featured units to help patients and their caregivers find the right fit.
Model | Flow Settings | Sound Level | Weight | Key Features |
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React Health Platinum 10 with SENSEO2 | Continuous 2–10 LPM | ~50 dBA | 52 lbs |
SENSEO2 purity sensor Built-in safety alerts Wheeled design High durability |
Philips Respironics Millennium M10 | Continuous 2–10 LPM | ~50 dBA | 53 lbs |
Humidifier-ready Twin-head compressor Integrated sieve canister High-grade casters |
Drive DeVilbiss 10 Liter Compact | Continuous 2–10 LPM | 49–53 dBA | 42 lbs |
Supports up to 50 ft tubing Built-in humidifier compartment Flow meter lock Digital hour meter |
Why Some Patients Might Require a Higher LPM Concentrator
While the standard for oxygen concentrators ranges between 0.5 and 5 LPM, and there are multiple devices at this level, some patients may require a higher oxygen output. There are many reasons why a patient might need up to 10 LPM. Here are a few possibilities:
Condition/Situation | Reason for Higher Oxygen Output |
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Severe Hypoxemia or Advanced Lung Disease | Ensures proper saturation during exertion or sleep for conditions like COPD or fibrosis. |
Cluster Headaches | Higher flows prescribed for acute relief during headache episodes. |
Tracheostomy | Provides humidified high-flow oxygen as prescribed for stoma care. |
Find the Right 10 Liter Home Oxygen Concentrator Today
Main Clinic Supply offers a carefully curated selection of 10-liter home oxygen concentrators built for high-demand oxygen therapy. Whether you need quiet operation, compact design, or real-time purity monitoring, we have a solution tailored to your prescription and lifestyle.
Need help choosing the best option? Our Oxygen Specialists are ready to assist. Call us today at 1-888-850-9017.
Speak To One Of Our Oxygen Specialists!


“This has been the best online buying experience I have ever done, unlike other places when I was shopping and reading reviews Main Clinic Supply answered the phone right away every time, my package said overnight before 10:30 AM, it was here 10.15 AM the next day! Can’t say enough good thing, they realize you need your oxygen now they get it to you fast!”
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