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A Comprehensive Comparison of Portable Oxygen Concentrators

Portable oxygen concentrators have become a vital medical device for individuals who require supplemental oxygen therapy. Technological advancements have made these devices more compact, lightweight, and efficient. In this comprehensive comparison, we will explore portable oxygen concentrators' role in healthcare, how they work, and the factors to consider when choosing the right one for your needs. Additionally, we will review the top portable oxygen concentrator brands and provide a detailed comparison of selected models based on size and weight, oxygen output, and battery life.

What this article covers:

Understanding Portable Oxygen Concentrators

Before we dive into the details, it is essential to have a solid understanding of what portable oxygen concentrators are and how they function. These devices are designed to extract oxygen from the surroundings, concentrate it, and continuously deliver it to the user. Unlike traditional oxygen tanks, which need to be refilled frequently, portable oxygen concentrators offer an endless supply of oxygen without the need for frequent replacements. The oxygen tank vs oxygen concentrator debate centers on this distinct advantage.

comparison portable oxygen concentrators

Portable oxygen concentrators have revolutionized the lives of individuals dependent on supplemental oxygen. They have made it possible for patients to maintain an active lifestyle without being tethered to an oxygen tank or confined to their homes. A common comparison made is the oxygen concentrator vs cylinder in terms of portability and convenience.

But how exactly do these devices work and what is their role in healthcare?

The Role of Oxygen Concentrators in Healthcare

Portable oxygen concentrators are crucial in healthcare, particularly for patients with respiratory conditions such as chronic obstructive pulmonary disease (COPD), asthma, and pulmonary fibrosis. These devices enable patients to receive the necessary amount of oxygen while independently carrying out their daily activities.

Furthermore, oxygen concentrators are often used in hospitals, ambulances, and healthcare facilities as a backup or alternative to traditional oxygen tanks. They provide a reliable and cost-effective solution for oxygen therapy to needy patients.

With the advancement of technology, portable oxygen concentrators have become smaller, lighter, and more efficient, making them even more accessible to patients and healthcare providers. The choice between a 5l vs 10l oxygen concentrator usually depends on the specific oxygen requirements of the patient.

How Portable Oxygen Concentrators Work

Portable oxygen concentrators utilize advanced technology to extract oxygen from the air. The device draws in ambient air through an inlet filter, removing impurities and other gases. The remaining oxygen-rich air is then compressed and passed through a molecular sieve bed, which separates nitrogen and other gas molecules from the oxygen.

The purified oxygen is then delivered to the user through a nasal cannula or mask, ensuring an adequate supply of oxygen for breathing. Meanwhile, the separated nitrogen and other gases are released back into the surrounding environment.

compare oxygen concentrators

This continuous process ensures an uninterrupted and efficient supply of oxygen, enabling individuals to maintain their oxygen saturation levels and improve their overall well-being.

Portable oxygen concentrators have various features to enhance user experience and convenience. Some of the choices patients might face include the simply go mini vs inogen g4 debate, which revolves around features and portability. These features may include adjustable flow rates, battery-powered operation, and compact designs allowing easy portability.

Some portable oxygen concentrators are equipped with sensors and alarms to alert users of low oxygen levels or other potential issues, ensuring their safety and peace of mind.

As technology advances, the future of portable oxygen concentrators looks promising. For some, the choice boils down to an oxygen conserving device vs concentrator, depending on the specific needs and lifestyle of the user. Researchers and manufacturers are constantly working on improving these devices' efficiency, reliability, and portability, aiming to enhance the quality of life for individuals with respiratory conditions.

In conclusion, portable oxygen concentrators have revolutionized the way individuals with respiratory conditions receive oxygen therapy. These devices provide a reliable and convenient solution, allowing patients to maintain an active lifestyle and improve their overall well-being. With their advanced technology and medical-grade oxygen supply, portable oxygen concentrators have become an indispensable tool in healthcare.

Factors to Consider When Choosing a Portable Oxygen Concentrator

When it comes to selecting the right portable oxygen concentrator, several factors need to be taken into account. These factors include size, portability, oxygen output, battery life, noise level, and more. Let's explore each of these factors in detail to help you make an informed decision.

portable oxygen concentrator comparisons

Size and Portability

One of the primary considerations when choosing a portable oxygen concentrator is its size and portability. The device should be compact and lightweight, allowing individuals to carry it comfortably during their daily activities. Some devices are designed to be worn on a belt or shoulder strap, while others can fit into a backpack or handbag. Selecting a portable oxygen concentrator that suits your lifestyle and mobility needs is crucial for maintaining independence and convenience.

Additionally, it's important to consider the device's dimensions and weight. Some concentrators are smaller and lighter than others, making them easier to transport. However, keep in mind that smaller devices may have limitations on oxygen output and battery life.

Oxygen Output

The oxygen output of a portable oxygen concentrator determines how much oxygen it can deliver to the user. Choosing a device that suits your prescribed oxygen flow rate is essential. Typically, oxygen concentrators offer a range of flow rates to accommodate varying patient needs. Ensuring that your chosen device can deliver the required amount of oxygen is essential for effective therapy.

Moreover, consider the device's oxygen delivery system. Some concentrators use pulse dose technology, delivering oxygen in short bursts when the user inhales. Others utilize continuous flow technology, providing a steady stream of oxygen regardless of the user's breathing pattern. Understanding your oxygen therapy requirements will help you select the most suitable concentrator.

Battery Life

Another critical factor to consider is the battery life of the portable oxygen concentrator. Patients relying on oxygen therapy need a device with a battery that can last throughout the day. Long battery life ensures that individuals can confidently go about their daily activities without worrying about running out of oxygen. Some devices also offer external battery options for extended usage or as a backup.

When evaluating battery life, take into account the device's oxygen flow rate and settings. Higher flow rates and continuous flow settings may consume more power, reducing the overall battery life. Choosing a concentrator with a battery duration that aligns with your daily routine and anticipated usage is advisable.

portable oxygen concentrators comparison chart

Noise Level

The noise level of the portable oxygen concentrator is an important consideration, especially for individuals who are sensitive to noise or wish for a quieter operation. Some concentrators operate silently, while others produce a low level of noise during operation. Selecting a device with a noise level that suits your preferences and environment will contribute to a comfortable user experience.

Furthermore, consider the noise level in relation to your activities and surroundings. A quieter device may be more suitable if you plan to use the concentrator in public spaces or while sleeping. On the other hand, if you primarily use it at home, noise level may be less of a concern.

By carefully considering these factors, you can choose a portable oxygen concentrator that meets your specific needs and enhances your quality of life. Remember to consult with your healthcare provider for personalized recommendations based on your medical condition and oxygen therapy requirements.

Review of Top Portable Oxygen Concentrator Brands

Now that we have explored the factors to consider when choosing a portable oxygen concentrator let's take a closer look at some of the top brands in the market.


Inogen is a renowned brand that offers a range of portable oxygen concentrators known for their reliability and performance. Their devices are compact, lightweight, and feature advanced technologies to ensure optimal oxygen delivery.

Inogen's commitment to innovation is evident in their product designs. They have incorporated cutting-edge features such as intelligent oxygen delivery systems that automatically adjust the oxygen flow based on the user's breathing patterns. This ensures efficient oxygen therapy and maximizes battery life, allowing users to stay active for longer periods without worrying about running out of oxygen.

Furthermore, Inogen is widely recognized for its exceptional customer support. Their knowledgeable and friendly customer service team is available round the clock to assist users with any queries or concerns. Whether it's troubleshooting technical issues or providing guidance on maintenance, Inogen's customer support ensures a seamless experience for their users.

portable oxygen concentrator comparison chart


Respironics, a division of Philips, is another prominent player in the portable oxygen concentrator market. Their devices are highly regarded for their durability, user-friendly interface, and excellent oxygen output.

Respironics understands the importance of user convenience and has incorporated intuitive controls and interfaces in their devices. This ensures that patients, regardless of their technological proficiency, can easily operate and adjust the oxygen settings according to their needs.

Moreover, Respironics offers a range of models, catering to different patient needs and requirements. Whether someone requires a compact and lightweight concentrator for travel or a more robust device for everyday use, Respironics has a suitable option to meet their needs.

O2 Concepts

O2 Concepts is a company that designs and manufactures portable oxygen concentrators (POCs). They strive to create innovative and reliable oxygen solutions for patients who require supplemental oxygen. Their products are designed for ease of use, and durability and to provide patients the highest level of freedom and independence.

Their two flagship POCs are the OxLife Independence and OxLife Liberity Portable Oxygen Concentrators, which provide a blend of continuous flow and pulse dose delivery options. These devices are known for their high oxygen output, robust design, and features aimed at providing users with a high level of mobility, including on the Oxlife Indepences, its built-in cart for easy transport.

Detailed Comparison of Selected Oxygen Concentrators

Best Overall Portable Oxygen Concentrator - Recommended by Main Clinic Supply

Inogen One G5 Portable Oxygen Concentrator 

The Inogen One G5 Portable Oxygen Concentrator is one of our favorite portable oxygen concentrators.

portable o2 concentrator comparison

At Main Clinic Supply, we offer a wide selection of top-tier POCs. Among them, the Inogen One G5 has won our acclaim as the leading portable oxygen concentrator currently available on the market.

Employing a unique proprietary technology, the Inogen One G5 rapidly and efficiently delivers oxygen. It is designed to ensure that oxygen is supplied within the initial 250 milliseconds of inhalation - the crucial time window where oxygen has the most significant effect on lung gas exchange. This system's triggering sensitivity allows it to detect breaths and promptly dispense oxygen during this vital period.

During sleep, it's normal for respiratory rates to diminish. Cleverly, the Inogen One G5 adapts to this physiological change by amplifying the volume of oxygen it delivers. Specifically, at a respiration rate of ten breaths per minute, it can deliver twice the oxygen compared to a respiration rate of 20 breaths per minute.

This innovative approach has been shown to effectively oxygenate patients during sleep, rest, and physical activity. For most individuals, oxygen delivery systems like the Inogen One can function as their primary oxygen delivery system across all usage scenarios.

The Inogen One is an adaptable, portable solution that is suitable for use in various settings, including homes, institutions, vehicles, and a range of mobile environments. This makes it a fantastic alternative for those looking to lessen their reliance on liquid oxygen systems and tanks.


  • Chatburn RL, Lewarski JS, McCoy RW. Nocturnal oxygenation using a pulsed-dose oxygen-conserving device compared to continuous flow. Respir Care. 2006 Mar;51(3):252-6. PMID: 16533414.
  • CHEST 1999 Vol.116(1):22-29

There is an option of 6 different settings to base your oxygen delivery on your needs or your activity. The maximum amount of oxygen that can be delivered per minute is 1260 ml, which is more than enough to meet most people's requirements. The Inogen One G5 POC is one of the lightest POCs we offer, weighing a minuscule 4.7 lbs. It is also one of the quietest POCs available, as its sound is only 38 dBA. 

This POC is also very small and compact. It is 8.15 inches tall, 7.19 inches long, and 3.26 inches wide, making it one of the smallest home oxygen concentrators.

This makes the Inogen One G5 the perfect portable oxygen concentrator for hiking, spending days out and about, or for someone who struggles to carry a heavy weight on their shoulders. 

Moreover, this POC stands out for its exceptional battery life, leading the pack among all POCs we offer. Once fully charged, the batteries can endure up to 9 hours, though this duration varies based on the selected setting and the user's level of physical activity. This feature makes this POC the perfect companion for a day filled with adventures, freeing you from the constraint of a limited outing duration.

oxygen concentrator comparison chart

To enhance its portability, we also offer a purpose-designed over-the-shoulder carry bag that snugly accommodates the Inogen One G5, enabling you to conveniently transport and carry it wherever you journey.

The easy-to-read LCD and its intuitive controls further simplify the operation of this device, making it user-friendly and accessible to virtually everyone.

The Inogen One G5 is FAA-approved, meaning you can safely use this portable oxygen concentrator for air travel without worrying about where or how you will receive oxygen during flights. 

This POC is compact, reliable, safe, easy to use and transport, and a device that will be able to meet all your supplementary oxygen needs. 

You can buy this portable oxygen concentrator on sale from us for an exceptionally reasonable price of $1995.00.

Why It's Great 

  • Six different flow settings 
  • Proprietary Oxygen Delivery
  • One of the lightest POCs around 
  • FAA approved for inflight use

Who It's Right For 

  • The elderly or sick individuals who are not able to carry heavy weights
  • People who are noise sensitive

Best Continous & Pulse Flow Portable Oxygen Concentrator

Philips Respironics SimplyGo Portable Oxygen Concentrator 

The SimplyGo POC has an LCD touch screen, enhancing its usability and making it accessible to everyone. The touch screen facilitates effortless switching among five distinct oxygen flow settings, tailored to your immediate oxygen needs.

Powered by both AC and DC, the SimplyGo POC includes a lithium-ion battery that integrates smoothly into the device. It offers the choice of a standard or extended battery, with the standard one providing up to 4.5 hours of service. The unit features a quick-change battery slot for swift and efficient battery replacement.

Notably, this POC has received FAA approval for air travel, enabling you to globe-trot while maintaining your oxygen therapy. An upgrade to one of our packages allows you to add a stylish carry bag with a shoulder strap, ensuring your SimplyGo POC is always at hand in a sleek and practical case.

comparison of portable oxygen concentrators

Among its standout features, this POC offers continuous flow, pulse dose oxygen delivery, and a Sleep Mode. In pulse mode, the SimplyGo detects your inhalation and promptly provides the necessary oxygen volume.

It delivers steady oxygen from 0.5 to 2 LPM in continuous flow mode. Sleep mode is essentially a pulse mode with enhanced sensitivity during sleep. If it fails to detect breath intake, it automatically shifts to continuous flow, supplying oxygen at 2 LPM.

The provision of both continuous flow and pulse mode is quite uncommon in POCs. Ordinarily, oxygen concentrators offering continuous flow are not portable, but this isn't the case with the Philips Respironics SimplyGo POC.

Weighing merely 10 lbs, the SimplyGo Mini is highly portable. It operates efficiently up to altitudes of 10,000 feet and in temperatures ranging from 41° F to 95° F.

Characterized by a sleek design, the Philips Respironics SimplyGo Portable Oxygen Concentrator offers reliability, lightweight convenience, portability, and user-friendliness.

Based on our hands-on experience, we assertively endorse it as one of the best portable oxygen concentrators offering both pulse and continuous flow oxygen available on the market. It can be procured from us at $2,295.00.

Why It's Great:

  • Offers both continuous flow and pulse dose modes

  • Five flow settings for pulse flow oxygen delivery

  • Three flow settings for continuous oxygen delivery

  • Lightweight, weighing only 10 pounds

  • Sleep mode guarantees uninterrupted oxygen supply during sleep

Who It's Best For:

  • Individuals with an active lifestyle

  • Those who need both continuous flow and pulse dose oxygen

  • Ideal for international users, given the extensive worldwide service centers

Best Continous & Pulse High- Flow Portable Oxygen Concentrator

O2 Concepts OxLife Independence Portable Oxygen Concentrator 

The O2 Concepts OxLife Independence Portable Oxygen Concentrator is different from all of the other POCs that have, and will be, mentioned in this article because it is the only one that comes with a rolling cart and an adjustable handle. 

comparison of oxygen concentrators

The option is to purchase an accessory carry bag or a wheelchair bag. The wheelchair bag allows it to clip onto your wheelchair so that it can be transported and taken anywhere you go. 

Like the Philips Respironics SimplyGo, the O2 Concepts OxLife Independence Portable Oxygen Concentrator employs continuous flow and pulse dose oxygen delivery mechanisms.

In its continuous flow mode, the O2 Concepts OxLife Independence POC can deliver up to a maximum of 3 LPM, with the minimum delivery being 0.5 LPM. When operating in pulse dose mode, this POC offers six varying settings.

You can easily manage these settings via an LCD screen that showcases a clean and intuitive design.

Robust, rechargeable batteries power the O2 Concepts OxLife Independence POC. In pulse dose mode, with the device delivering 2 LPM of oxygen or less, the batteries can sustain for about 5 hours. If the device operates in continuous flow mode, the batteries can last for slightly over an hour, given that it provides 2 LPM of oxygen or less.

But you won't have to worry about this too much, as the batteries can be charged from a standard AC power supply, and our POC also comes with a DC power supply and adapter. This means you can also charge and use your portable oxygen concentrator in the car. You can also continue oxygen delivery while the batteries charge. There is also an optional external battery charger to have plenty of batteries charged and ready to go. 

oxygen concentrator sizes

This POC's ability to be approved by the FAA for use on most airplanes and cruise ships makes it an excellent travel companion. Thanks to its compact size, it fits effortlessly under an airplane seat.

The only limitation could be activities like hiking due to its size and weight. It might not be the best choice to lug around while climbing mountains given that it's one of the heavier and larger POCs.

The O2 Concepts OxLife Independence POC weighs in at 16.7 lbs and measures 20.2 inches in height, 10.9 inches in width, and 8 inches in depth.

However, this POC operates quietly, ensuring minimal disturbance to those around you. Plus, it's capable of functioning at altitudes of up to 13,123 feet.

You can purchase this POC from us for $2,450.00, and it comes with a 5-year warranty.

Why It's Exceptional:

  • It includes a built-in rolling cart
  • It offers the highest available continuous flow of oxygen in a POC
  • It fits snugly under an airplane seat

Ideal For:

  • People who prefer not to carry their POC on their shoulders
  • People who require a higher flow of oxygen delivery
  • Frequent travelers

Best Carry Continous & Pulse Flow Portable Oxygen Concentrator

O2 Concepts OxLife Liberty Portable Oxygen Concentrator 

While there are similarities between this POC and the O2 Concepts OxLife Independence POC, there are some noticeable differences, too. 

Firstly, while both the Independence and the Liberty have the option for continuous flow mode or pulse dose mode, the amount of oxygen they can deliver differs. 

When the Liberty POC is in continuous flow mode, it can deliver a maximum constant flow oxygen output of 1.5 LPM compared to the Independence POC's 3 LPM. In pulse dose mode, there are nine different settings compared to the Independence POC's 6. 

Using both modes makes this POC versatile and reliable, as you can customize and alter the oxygen delivery based on your needs and activity levels. 

The O2 Concepts OxLife Liberty Portable Oxygen Concentrator also does not have a built-in rolling cart like the Independence POC. Still, it can rather be carried around in an over-the-shoulder bag. 

home oxygen concentrator comparison chart

Based on our observations, this device is much more compact and lightweight, which is better for those who are always on the go and are fairly active. 

The Liberty POC weighs 6.35 lbs, has a height of 9.9 inches, a width of 9.9 inches, and a depth of 3.8 inches. 

After the battery has been charged, it lasts approximately 4.5 hours. These rechargeable batteries can be charged by an AC power supply that plugs into the wall, or they can be charged in the car using the DC car charger that comes with it. 

The user-friendly LCD screen and control panel makes this POC extremely easy to use. It makes it more accessible to people who do not want to mess with complicated technology. 

This POC is FAA approved to be used on all airlines. If you want to know what airlines allow portable oxygen concentrators exactly, check out our guide.

This POC is perfect for someone always on the go and looking for a small, compact, reliable, and versatile POC to help them with their oxygen needs. 

You can purchase the O2 Concepts OxLife Liberty Portable Oxygen Concentrator for $2 195.00, with a 3-year warranty. 

oxygen concentrators comparison

Why It's Great 

  • Has a DC car charger
  • Long-lasting batteries
  • Nine different flow settings 

Who It's Right For 

  • People require more pulse oxygen settings and continuous flow oxygen.


A comprehensive comparison of portable oxygen concentrators is crucial to make an informed decision about the device that suits your requirements. Understanding how these devices work and the factors to consider, such as size and portability, oxygen output, battery life, and noise level, can help you choose the best device for your needs. Additionally, considering top brands like Inogen, Respironics, and Invacare, along with a detailed comparison of selected models, allows you to make a well-informed decision based on your individual preferences and medical requirements. With a suitable portable oxygen concentrator, you can regain your independence, maintain an active lifestyle, and improve your overall quality of life.

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