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Best Portable Oxygen Concentrator

In today's fast-paced world, many people have no choice but to maintain an active and on-the-go lifestyle. But, this can be pretty challenging for people who suffer from chronic respiratory problems. 

Many traditional oxygen therapy methods can limit your ability to partake in everyday activities such as hiking, flying on airplanes, or going to the shops. 

Thankfully, medical technology has evolved and paved the way for portable oxygen concentrators, a game-changer for those who rely on supplemental oxygen. 

Portable oxygen concentrators (POCs) allow those with chronic respiratory diseases to not be held back by their condition and live their lives to the fullest. 

In this article, we will discuss the best portable oxygen concentrators available from us, which will help enable you to live the life you have always wanted. 

What this article covers:

Best Portable Oxygen Concentrator 

Best Overall Portable Oxygen Concentrator

Inogen One G5 Portable Oxygen Concentrator 

The Inogen One G5 Portable Oxygen Concentrator is one of our favorite portable oxygen concentrators on the market. Here at Main Clinic Supply, we stock all the top POCs; overall, we rated this as the best portable oxygen concentrator on the market today.

consumer reports best portable oxygen concentrator

The Inogen One G5 portable oxygen system uses proprietary technology to deliver oxygen quickly and efficiently. It ensures that oxygen is delivered within the first 250 milliseconds of inspiration when oxygen most affects lung gas exchange. The system also uses triggering sensitivity to detect breaths quickly and deliver oxygen within the critical period.

During periods of sleep, respiratory rates typically decrease. The Inogen One G5 actively responds to this changing physiology by increasing the amount of oxygen delivered. At ten breaths per minute, Inogen One G5 provides double the amount of oxygen when the breathing rate is 20 breaths per minute.

This technology has been proven to oxygenate patients during sleep, rest, and exertion. In fact, for most people, oxygen systems like the Inogen One can be used as a primary oxygen delivery system for all modes of use.

The Inogen One is a portable system that can be used in a home, institution, vehicles, and various mobile environments. It is an excellent option for people who want to reduce their dependence on liquid oxygen systems and tanks.


  • Chatburn RL, Lewarski JS, McCoy RW. Nocturnal oxygenation using a pulsed-dose oxygen-conserving device compared to continuous flow. Respir Care. 2006 Mar;51(3):252-6. PMID: 16533414.
  • CHEST 1999 Vol.116(1):22-29

There is an option of 6 different settings so that you can base your oxygen delivery on your needs or the activity you are doing. The maximum amount of oxygen that can be delivered per minute is 1260 ml, which is more than enough to meet most people's requirements. 

The Inogen One G5 POC is one of the lightest POCs we offer, weighing a minuscule 4.7 lbs. It is also one of the quietest POCs available, as the sound it produces is only 38 dBA. 

This POC is also very small and compact. It is 8.15 inches tall, 7.19 inches long, and 3.26 inches wide, making it one of the smallest home oxygen concentrators.

This makes the Inogen One G5 the perfect portable oxygen concentrator for hiking, spending days out and about, or for someone who struggles to carry a heavy weight on their shoulders. 

Additionally, this POC has incredible battery life and is the best out of all the POCs we offer. Once the batteries are charged, they can last up to 9 hours, depending on the setting and the user's exertion level. This makes this POC ideal for an adventurous day out, as you don't need to worry about being limited to only being out for a few hours. 

best portable oxygen concentrators

You can also purchase an over-the-shoulder carry bag from us that the Inogen One G5 fits perfectly into. This will allow you to transport it and easily take it wherever you go.  

The LCD is easy to read and uses straightforward controls, making it possible for almost anyone. 

The Inogen One G5 is FAA-approved, meaning you can safely use this portable oxygen concentrator for air travel and not have to worry about where or how you will receive oxygen during flights. 

This POC is compact, reliable, safe, easy to use and transport, and a device that will be able to meet all your supplementary oxygen needs. 

You can buy this portable oxygen concentrator on sale from us for an exceptionally reasonable price of $1995.00.

Why It's Great 

  • Six different flow settings 
  • Proprietary Oxygen Delivery
  • One of the lightest POCs around 
  • FAA approved for inflight use

Who It's Right For 

  • The elderly or sick individuals who are not able to carry heavy weights
  • People who are noise sensitive

Best Continous Flow Portable Oxygen Concentrator

Philips Respironics SimplyGo Portable Oxygen Concentrator 

The Philips Respironics SimplyGo Portable Oxygen Concentrator is a reliable and user-friendly POC. 

It boasts an LCD touch screen, making it very easy to use and accessible for everyone. This touch screen allows you to easily switch between the five different oxygen flow settings, depending on your current oxygen requirement.

portable oxygen concentrator reviews

The SimplyGo POC can run off AC and DC power and has a lithium-ion battery that fits seamlessly into the POC. there is an option of using a standard or extended battery. Using the standard battery can last up to 4.5 hours, and features a quick change battery slot to refresh with a new charged battery. 

This POC has been approved for air travel by the FAA. This means you can fly around the world and continue your oxygen therapy.

There is the option of adding a classy-looking carrying bag with a shoulder strap to your purchase if you upgrade to one of our packages. This means you can take your SimplyGo POC everywhere in a convenient good-looking case.

One of the best things about this POC is that it offers continuous flow and pulse dose oxygen delivery. Additionally, it also provides Sleep Mode

When it is in pulse mode, the SimplyGo detects when you take a breath and delivers the necessary oxygen volume. 

It delivers continuous oxygen from 0.5 to 2 LPM when in continuous flow mode. Sleep mode is basically pulse mode with increased sensitivity for when you are sleeping. Suppose it does not sense any breath intake. In that case, it will automatically switch to continuous flow and deliver oxygen at 2 LPM.

It is very rare for a POC to have the option of both continuous flow and pulse mode. Often, oxygen concentrators that offer continuous flow oxygen are not portable. This is not the case with the Philips Respironics SimplyGo POC. 

The SimplyGo Mini only weighs 10 lbs.

This POC works up to altitudes of 10,000 feet and between temperatures of 41° F to 95° F.

The Philips Respironics SimplyGo Portable Oxygen Concentrator has a sleek and attractive design; it is reliable, lightweight, easy to carry around, and extremely user-friendly.

Based on our first-hand experience, we can confidently say that it is one of the best portable oxygen concentrators with pulse and continuous flow oxygen on the market. You can purchase it from us for $2,295.00.

what is the best portable oxygen concentrator

Why It's Great 

  • Has a continuous flow and pulse dose modes
  • Five flow settings for pulse flow oxygen delivery
  • Three flow settings for continuous oxygen delivery
  • Lightweight at only 10 pounds
  • Sleep mode that ensures oxygen will always be delivered when you are sleeping 

Who It's Right For 

  • People who are often on the go
  • People who require both continuous flow and pulse dose oxygen 
  • Ideal for those using outside the USA, more service centers worldwide

Best Continous Flow and Pulse Flow Portable Oxygen Concentrator

O2 Concepts OxLife Independence Portable Oxygen Concentrator 

The O2 Concepts OxLife Independence Portable Oxygen Concentrator is different from all of the other POCs that have, and will be, mentioned in this article because it is the only one that comes with a rolling cart and an adjustable handle.

consumer reports best home oxygen concentrator

The option is to purchase an accessory carry bag or a wheelchair bag. The wheelchair bag allows it to clip onto your wheelchair so that it can be transported and taken anywhere you go. 

Similarly to the Philips Respironics SimplyGo, the O2 Concepts OxLife Independence Portable Oxygen Concentrator makes use of both continuous flow and pulse dose oxygen delivery methods. 

In continuous flow mode, the O2 Concepts OxLife Independence POC has a maximum output of 3 LPM, with the lowest output of 0.5 LPM. This POC has six different settings when it is in pulse dose mode. 

These settings can be controlled by an LCD screen with a simple and straightforward design. 

The O2 Concepts OxLife Independence POC runs on long-lasting, rechargeable batteries. When the POC is on pulse dose mode and delivering 2 LPM of oxygen or less, the batteries will last approximately 5 hours. 

If it is in continuous flow mode, the batteries can last just over an hour if delivering 2 LPM of oxygen or less. 

But you won't have to worry about this too much, as the batteries can be charged from a standard AC power supply, and our POC also comes with a DC power supply and adapter. This means you can also charge and use your portable oxygen concentrator in the car. You can also continue oxygen delivery while the batteries charge. There is also an optional external battery charger to have plenty of batteries charged and ready to go. 

what is the best portable oxygen concentrator on the market

This, along with the fact that it is FAA approved and can go on most airplanes and cruise ships, means that this POC can go with you wherever you go. Because of how compact it is, it also fits perfectly under an airplane seat. 

The only activity that may be found difficult using it is hiking. It is obviously not ideal to pull it around when you are walking up a mountain. Unfortunately, it is one of the heavier and bigger POCs.

The O2 Concepts OxLife Independence POC weighs 16.7 lbs, is 20.2 inches high, 10.9 inches wide, and has a depth of 8 inches. 

This POC is extremely quiet, though, which is beneficial as it won't disturb anyone around you when it is on. Another positive is that it can also work in altitudes up to 13,123 feet. 

You can purchase this POC from us for $2 450.00, and it comes with a 5-year warranty. 

Why It's Great 

  • It comes with a built-in rolling cart 
  • The highest continuous flow of oxygen available in a POC
  • It fits under an airplane seat

Who It's Right For 

  • People who don't want to carry their POC on their shoulders
  • People who require a higher flow of oxygen delivery
  • People who travel a lot 

O2 Concepts OxLife Liberty Portable Oxygen Concentrator 

While there are similarities between this POC and the O2 Concepts OxLife Independence POC, there are some noticeable differences, too. 

Firstly, while both the Independence and the Liberty have the option for continuous flow mode or pulse dose mode, the amount of oxygen they can deliver differs. 

When the Liberty POC is in continuous flow mode, it can deliver a maximum constant flow oxygen output of 1.5 LPM compared to the Independence POC's 3 LPM. Additionally, in pulse dose mode, there are nine different settings compared to the Independence POC's 6. 

Using both modes makes this POC versatile and reliable, as you can customize and alter the oxygen delivery based on your needs and activity levels. 

The O2 Concepts OxLife Liberty Portable Oxygen Concentrator also does not have a built-in rolling cart like the Independence POC. Still, it can rather be carried around in an over-the-shoulder bag. 

best portable oxygen machine

Based on our observations, this device is much more compact and lightweight, which is better for those who are always on the go and are fairly active. 

The Liberty POC weighs 6.35 lbs, has a height of 9.9 inches, a width of 9.9 inches, and a depth of 3.8 inches. 

After the battery has been charged, it lasts approximately 4.5 hours. These rechargeable batteries can be charged by an AC power supply that plugs into the wall, or they can be charged in the car using the DC car charger that comes with it. 

The user-friendly LCD screen and control panel makes this POC extremely easy to use. It makes it more accessible to people who do not want to mess with complicated technology. 

This POC is FAA approved to be used on all airlines. If you want to know what airlines allow portable oxygen concentrators exactly, check out our guide.

This POC is perfect for someone always on the go and looking for a small, compact, reliable, and versatile POC to help them with their oxygen needs. 

You can purchase the O2 Concepts OxLife Liberty Portable Oxygen Concentrator for $2 195.00, with a 3-year warranty. 

Why It's Great 

  • Has a DC car charger
  • Long-lasting batteries
  • Nine different flow settings 

Who It's Right For 

  • People require more pulse oxygen settings and continuous flow oxygen.


Our #1 ranked recommendation for "The Overtall Best Portable Oxygen Concentrator" is the Inogen One G5

Overall, the Inogen One G5 is an excellent option for people who need a portable oxygen concentrator. It's lightweight, quiet, long-lasting, and versatile. If you're looking for a reliable and easy-to-use portable oxygen concentrator, the G5 is a great choice.

best portable oxygen machines

Here are some specific examples of when the advantages of the Inogen 1 G5 concentrator would be most beneficial:

  • If you are active and need to carry your oxygen concentrator, the G5's lightweight design would be a significant advantage.
  • The G5's quiet operation will be appreciated if you live in a noisy environment.
  • If you have a high oxygen requirement, the G5's six-flow settings will allow you to customize your therapy to meet your needs.
  • If you travel frequently, the G5's FAA approval would mean that you can take it with you on airplanes.

Our #1 ranked recommendation for "The Best Constant Flow Portable Oxygen Concentrator."

The Respironics SimplyGo portable concentrator is a versatile and innovative unit with unique features that make it an excellent choice for many oxygen therapy users. The ability to deliver both pulse dose and continuous flow oxygen, with its lightweight design and long battery life, make the SimplyGo an excellent option for people who want to maintain their Independence and mobility while receiving oxygen therapy.

In addition to its technical specifications, SimplyGo has several other features that make it a user-friendly and attractive option. The sleek white design is stylish and discreet, and the included carrying case and cart make it easy to transport. The SimplyGo is also FAA-approved for in-flight use, so you can take it anywhere.

The Respironics SimplyGo portable concentrator is an excellent choice for a lightweight, versatile, and user-friendly oxygen therapy. If you are considering oxygen therapy, the SimplyGo is worth considering.

  • The SimplyGo is FAA-approved for in-flight use so you can take it with you on your travels.
  • A two-year warranty backs the SimplyGo.
  • The SimplyGo has service centers worldwide if you travel outside of the United States.

Our #1 ranked recommendation for "The Best Constant Flow Portable and Pulse Flow Oxygen Concentrator."

Suppose you require a high continuous flow of oxygen and you travel frequently. In that case, the O2 Concepts OxLife Independence Portable Oxygen Concentrator is a good option. If you are looking for a more compact and lightweight POC with more pulse oxygen settings but still with a lower continuous oxygen flow option, the O2 Concepts OxLife Liberty Portable Oxygen Concentrator is a good choice.

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