The Best Portable Oxygen Concentrators: 2025 Rankings

Main Clinic Supply strives to offer customers a variety of portable oxygen concentrators, including many with portable form factors. Still, with so many options, which are the best models for an active lifestyle? Our selection of the top five portable oxygen concentrators is designed to help identify the model that most effectively aligns with individual oxygen therapy requirements.

• Weight (30%): Oxygen tanks can be heavy, but in many cases, portable oxygen concentrators reduce weight by using intelligent pulse flow technology. Still, weight varies significantly across product lines, so we factored in this criterion for our guide.
• Sound Level During Operation (20%): Portable concentrators are designed to run relatively quietly, but some produce more sound than others. We examined our five competitors and judged the decibels (dBA) each produced while operating.
• Battery Life (25%): Portability would be relatively useless if a portable oxygen concentrator only ran for an hour or so. For this criterion, we evaluated the battery life of each concentrator to see which one lasted the longest on a charge.
• Pulse Flows (25%): While some of our products use continuous flow output, which can reduce the operational time of a portable concentrator, each also has pulse flow, on-demand output settings. We evaluated the range of pulse flow settings each concentrator uses.

Top Five Portable Oxygen Concentrators

Rank	Product	Weight	Sound Level	Battery Life	Pulse Flows
#1	Rhythm P2-E6 Portable Oxygen Concentrator	4.3 pounds	About 38 dBA	Up to 5.4 hours	1 to 6
#2	Inogen One G4 Portable Oxygen Concentrator	2.8 pounds	About 40 dBA	Up to 5 hours	1 to 3
#3	Inogen Rove 6 Portable Oxygen Concentrator	4.7 pounds	About 37 dBA	Up to 12 hours	1 to 6
#4	CAIRE SeQual Eclipse 5 – Portable Oxygen Concentrator	18 pounds	48 dBA (continuous), 40 dBA (pulse)	Up to 5.4 hours	1 to 9
#5	Oxlife Liberty2 – True Continuous Flow Portable Oxygen	7.8 pounds	60.7 dBA (continuous), 58.7 dBA (pulse)	Up to 4.5 hours	1 to 10

The Best Portable Oxygen Concentrators: Descriptions & Reviews

1. Rhythm P2-E6 Portable Oxygen Concentrator

Best Overall Portable Oxygen Concentrator

• Weight: 4.3 pounds
• Sound Level: 38 dBA
• Battery Life: Up to 5.4 hours
• Pulse Flows: 1 to 6

When it comes to portable oxygen concentrators, the Rhythm P2-E6 stands out as the most well-rounded. It’s the second lightest concentrator in the guide and has a good range of pulse flow settings. It also has a moderate battery life that is augmented by the ability to “hot swap.” It only takes about four hours to fully charge the P2-E6, and it’s approved by the Federal Aviation Administration (FAA) for airplane travel.

What Customers Are Saying
While some users noted the lack of a continuous flow option, most love the lightweight form factor of the Rhythm P2-E6. Many were also pleased that this is an FAA-accepted portable oxygen concentrator.

2. Inogen One G4 Portable Oxygen Concentrator

Best Lightweight Form Factor Portable Oxygen Concentrator

• Weight: 2.8 pounds
• Sound Level: 40 dBA
• Battery Life: Up to 5 hours
• Pulse Flows: 1 to 3

At less than three pounds, this device is lighter than most purses. Even with the extended battery, the device only weighs about 3.3 pounds. It also features an easy-to-read and interpret user interface and offers charging options for AC and DC (12V) power supplies. At only 40 dBA, this is also a device that’ll run at about the same volume as a quiet conversation.

What Customers Are Saying
While some have complained about reduced battery life at higher flow settings, most agree that the Inogen One G4 is a great portable oxygen concentrator. It’s also noted to be very easy to use and to have a very readable screen, even in low-light or high-glare situations.

3. Inogen Rove 6 Portable Oxygen Concentrator

Best Portable Oxygen Concentrator for Battery Life

• Weight: 4.7 pounds
• Sound Level: 37 dBA
• Battery Life: Up to 12 hours
• Pulse Flows: 1 to 6

The Inogen Rove 6 can run for up to 12 hours on a single charge. This is uncommon in the portable oxygen concentrator industry, and it helps users have longer outings with fewer battery swaps. This product has six pulse flow settings, and the software selects the flow the user needs. This is also the quietest portable oxygen concentrator in this guide.

What Customers Are Saying
With 12 hours of battery life, many users appreciate the freedom that the Inogen Rove 6 provides. Some have also noted that its daily operation is very quiet, even when using the concentrator at night.

4. CAIRE SeQual Eclipse 5 – Portable Oxygen Concentrator

Best Portable Oxygen Concentrator for Urban Environments

• Weight: 18 pounds
• Sound Level: 48 dBA (continuous), 40 dBA (pulse)
• Battery Life: Up to 5.4 hours
• Pulse Flows: 1 to 9

Even the lightest portable oxygen concentrators can become heavy when used for extended periods, which is why there are wheeled variations like the CAIRE SeQual Eclipse 5. While having wheels is useful in paved areas, its larger wheels can also easily be used in uneven or rough terrain environments. It also has continuous and pulse dose settings. This model is even CPAP compatible.

What Customers Are Saying
Many users report that the combined continuous and pulse flows for this model are very advantageous for those who need these options. Also, some have stated that the battery duration of up to 3.7 hours on continuous flow is a significant benefit of the SeQual Eclipse 5.

5. Oxlife Liberty2 – True Continuous Flow Portable Oxygen

Best Portable Oxygen Concentrator with Both Continuous and Pulse Flows

• Weight: 7.8 pounds
• Sound Level: 60.7 dBA (continuous), 58.7 dBA (pulse)
• Battery Life: Up to 4.5 hours (up to 3.25 hours on continuous flow)
• Pulse Flows: 1 to 10

When many think of portable oxygen concentrators, pulse mode comes to mind as a way of increasing the device’s portability. With the Oxlife Liberty2, there are both continuous and pulse flow modes, helping provide oxygen during the day and night. While this one has a slightly higher sound level, with the sound reaching 60 decibels, the relatively lightweight design and output options add value to the product. Even on continuous flow, up to 3.25 hours of battery life is possible with the Liberty2.

What Customers Are Saying
The 10 pulse flow settings on this portable oxygen concentrator are often quoted as a major advantage by users. Also, many mention the portability of this device, while having multiple flow options is unique and very useful.

The Best Portable Oxygen Concentrators for Pulse Flow Settings

Ranking	Product	Available Flow Settings
#1	Oxlife Liberty2	1 to 10
#2	CAIRE SeQual Eclipse	1 to 9
#3	Inogen Rove 6	1 to 6
#4	Rhythm P2-E6	1 to 6
#5	Drive Devilbiss iGO2	1 to 5

The Best Portable Oxygen Concentrators for Battery Durations

Ranking	Product	Maximum Battery Duration
#1	CAIRE Freestyle Comfort	16 hours
#2	Inogen One G5	13 hours
#3	Inogen Rove 6	12 hours
#4	Inogen One G3	10 hours

For assistance choosing the best portable oxygen concentrator for you, call us at 1-800-775-0942.